ABSTRACT

Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, mol

chapter 1|26 pages

Animal Models of Depression

chapter 5|22 pages

Development of Brain Monoaminergic Systems

chapter 7|28 pages

Serotonergic Pathways in Depression

chapter 8|14 pages

Noradrenergic System in Depression

chapter 9|18 pages

Glutamatergic System and Mood Disorders

chapter 11|24 pages

Opioid System and Depression

chapter 14|24 pages

Depression and Cytokine-Regulated Pathways