ABSTRACT
This chapter reviews the preoperative diagnosis of extraprostatic extension-specifically seminal vesical invasion-in primary prostate adenocarcinoma. In a study conducted by Raskolnikov et al. on multiparametric magnetic resonance imaging (mpMRI) detection of extraprostatic extension, specificity was 73.9% with a negative predictive value of 82.8%. The study and review of seminal vesicle invasion in the clinical setting is highly important, but does not come without challenges. In brief, an mpMRI-transrectal ultrasound (TRUS) fusion-guided biopsy combines the high spatial resolution provided by mpMRI with the real-time imaging of the ultrasound during biopsy. Using TRUS-guided biopsy as the standard of reference, Roy et al. evaluated the sensitivity in the detection of post-RT local prostate cancer recurrence of the three types of functional magnetic resonance imaging. Cancer contained within the prostate is most often treated with radical prostatectomy. In this procedure, the prostate is excised along with the seminal vesicles and portions of the vas deferens.
