ABSTRACT
Consumption of plant derivatives (whole plant, extracts, and active compounds) is increased worldwide because they are part of nutritional supplements, nutraceuticals, or herbal products. The main reason to consume these types of products is to preserve health since plants contain compounds with biological properties to treat various diseases. Their consumption is associated with conditions associated with metabolic syndrome and aging. For this reason, many plant derivatives are used as antiobesogenic, antidiabetic, anticholesterolemic, and energetic. Additionally, some plants are used to treat infections or inflammatory diseases. Unfortunately, consumers and suppliers do not know the mechanisms of action and interactions of these products. However, the insufficiency of governmental regulation systems 332around the world increases the risk of adverse effects. Although there is a scientific breakthrough in the effectiveness and toxicity of a large number of medicinal plants, this information is not described on the label of the products that marketed. Therefore, regulatory agencies should consider their inclusion as well as the dosage. Pharmacokinetics and bioavailability studies of the active compounds from plants must be carried out to ensure their efficacy and safety.
