ABSTRACT
Primary cutaneous angiosarcoma is one of the most aggressive skin tumors and carries a very poor prognosis. It most frequently affects the face, scalp and neck of elderly individuals, and men are affected more than women. Clinically, angiosarcoma presents asymptomatically as a hematoma-like lesion, violaceous plaques or nodules. Often the lesions of angiosarcoma are multifocal and extend beyond the clinically identifiable borders of the lesion(s). Its initially indolent clinical presentation explains the frequently late diagnosis that, together with its typically multifocal pattern and poor delimitation, often makes surgery difficult. On dermoscopy angiosarcoma shows structureless erythematous-violet areas intermingled with yellow globules, pink-violet steam-like areas; radiation-induced angiosarcoma is characterized by homogenous structureless whitish-pink areas. They all show combinations of red, purple and blue colors and white lines.
