ABSTRACT
The human gene encoding APE1 maps to chromosome 14 at location 14q11.2 (https://www.ncbi.nlm.nih.gov/). The APE1 gene is comprised of four introns and fi ve exons, spanning 2.64 kilobases. The 5′ fl anking region (–890 bp) is located in a CpG island and lacks typical TATA and CAAT boxes, but contains TATA-and CAAT-like sequences and putative transcriptional factor recognition sites (Akiyama et al. 1994).
