ABSTRACT

The goal of drug delivery system approaches formulations, technologies, and systems for transporting a pharmaceutical compound in the body that is required to achieve safety for its desired therapeutic effect. Drugs are compounds that cause physiological change in the body, and the dose level of a drug determines whether it will act as medicine or poison. Drug delivery technologies modify drug release profile, absorption, distribution, and elimination for the benefit of improving product efficacy and safety, as well as patient convenience and compliance. Drug stability is an important factor because a drug in the solid state undergoes degradation at a much slower rate than a drug in solution. Drug metabolism is a process which may result in pharmacologically active, inactive, or toxic metabolites, which involves the enzymatic conversion of therapeutically important chemical species to a new molecule inside the human body.