ABSTRACT
Insulin.is.a.hormone.whose.major.function.is.to.reduce.blood.glucose..Insulin.resistance.is.a.state. wherein.the.body.loses.its.response.to.insulin..It.has.a.high.prevalence.in.obese.subjects.and.aging. people..The.main.damage.from.insulin.resistance.is.development.of.type.2.diabetes.and.cardiovascular.diseases.(CVD)..Often.associated.with.metabolic.syndrome,.insulin.resistance.was.discovered. 70.years.ago.by.Himsworth.[1]..The.clinical.evidence.of.insulin.resistance.was.that.diabetic.patients. lost.response.to.regular.dose.of.insulin..A.higher.dose.of.insulin.was.required.to.control.the.blood. glucose.in.these.patients.
