The methodology of scientific research programmes has attracted many admirers but few followers. The fate of Proofs and Refutations is still more paradoxical. Widely praised, it has enjoyed very little serious scholarly attention. This is perhaps because, unlike the methodology of scientific research programmes or Kuhn’s scientific revolutions, Proofs and Refutations does not offer a simple logical scheme for philosophers to apply more or less mechanically to the history of any given discipline. Proofs and Refutations is, perhaps, too complex and ambiguous to be the first of a genre. The aim of this chapter is to suggest some reasons for the reception of Lakatos’ work and to speculate a little regarding future developments.