ABSTRACT

The rate of substrate oxidation varies considerably during the day, being dictated by the body’s need to regenerate the adenosine triphosphate (ATP) used in carrying out its metabolic functions, in digesting and storing nutrients, in moving, and in performing physical tasks. The amount of heat generated is generally sufficient to allow maintenance of body temperature by regulation of heat dissipation, aided when necessary by measures seeking to maintain comfort through appropriate clothing and control of environmental temperatures. Situations where substrate oxidation is activated for the sake of thermogenesis are avoided as much as possible.