ABSTRACT
Example 9.8: During a pharmacokinetic study it was found that a drug is removed from the body exclusively by biotransformation and that the relationship expressing the decrease of the drug concentration in plasma is
where Vmax=0.60 (µg/ml)/h and KM=0.10 µg/ml. Calculate the time required for the decline of drug concentration from 30 to 18 µg/ml.
