ABSTRACT

Several questions have to be answered by refractive surgeons performing laser subepithelial keratomileusis (LASEK) surgery. Is the epithelial sheet viable after alcohol injury? What is the mechanism of epithelial detachment after alcohol application? Can the detached epithelium readhere after stroma injury? The aim of this chapter is to describe the key component of corneal epithelium to the stroma and to provide insight into the role of these molecules in governing the performance of LASEK as well as healing after LASEK.