ABSTRACT

The aerobic bioreactor is a device that brings three phases, liquid, air, and solid cell suspension, in intimate contact with each other and ensures adequate transfer rates of nutrients from the gas phase to the solid phase of cells. The mass transfer rates of necessary ingredients for growth and multiplication of cells are largely dependent on the area available for mass transfer and hydrodynamic conditions existing in the reactor. The relative velocities between different phases decide the efficiency of the transfer, while dispersion of gas either in the form of small bubbles and that of cells can provide the necessary area for mass transfer.