ABSTRACT

A nutrient is defined as any substance that has nutritious qualities, i.e., that

nourishes or promotes growth, and one that can be metabolized by an organism to

give energy and build tissue. In this chapter a nutrient is assumed to be an amino

acid, carotenoid, vitamin C, vitamin E, and other antioxidants such as polyphenols

(Fig. 1 shows the structures of some important antioxidants discussed in chapter).

While carotenoids, vitamin E, and vitamin C are often regarded as our most

important dietary antioxidants, little is known of their possible interactions. The

aim of this chapter is to discuss such interactions and to suggest how these may

explain possible synergistic protective effects as well as how deleterious effects

could arise. The carotenoids we consume, from our foods, food colorants, and

possibly as dietary supplements, are thought to be antioxidants both by quenching

singlet oxygen and by scavenging free radicals. This chapter concerns free radical

reactions; readers interested in singlet oxygen may consult recent reviews (1,2) and

the recent study of singlet oxygen quenching by carotenoids in liposomes (3).