ABSTRACT

At the beginning of this new millennium, the pharmaceutical industry is facing many

challenges in relation to the rapid and endless growth and aging of the world

population, and a growing gap between health care systems in industrialized and

developing countries. While higher and higher quality standards are required by authorities and consumers, andmassive low-cost supply of drugs is strongly demanded

by developing countries, it appears more andmore difficult to introduce innovative new

drugs and to improve the therapeutic efficacy against numerous pathologies. Further-

more, the industry must also make a continuous effort to move to environmentally

friendly processes.