ABSTRACT

The ideal renal cryoablative procedure has the relatively simple goal of freezing a desired lesion within the kidney to produce a predictable area of tissue death. The overall goal is to destroy a predetermined amount of tissue with a normal rim of renal parenchyma, thus recreating, as much as possible, surgical extirpation.1 Significant and rapid advances in the technology responsible to produce rapid tissue freezing have served to improve accuracy and predictability for this technique. In addition, our understanding of cryobiology and the direct and indirect mechanisms of cryogenic tissue injury have also improved.