ABSTRACT
Amine salts, like carboxylic acid salts (Section J3), are usually water soluble. As the amine group is a common feature of drug molecules, drugs are often administered as the amine salt to ensure that the drug is absorbed;
Morphine (water insoluble)
Morphine sulphate (water soluble)
H 2 SO
HO
N
O
HO
HO
N
O
HO
H
Perhaps the most important reaction involving amines is that which results in amide formation (Section J3) (Figure 2).
