We hope that we have helped you to think about men’s behavior in a new way, based on a gendered view of depression. Unfortunately, masculine depression is not only destructive in the context of emotional relationships. It also damages men’s physical health and lowers the quality of both men’s and women’s lives. In this chapter, we will speak both descriptively and prescriptively about men’s physical health issues. Our emotional lives infl uence our physical well being and vice versa. Modern medicine and health psychology are exploring the cutting edge of this connection, and we will review some of the literature in these areas.