ABSTRACT

The potential impact of an abnormal paternal genome on reproductive outcome is unquestionably less than that of its female counterpart. The importance of the egg is best illustrated by the plethora of studies relating female age to pregnancy outcome.1,2 Furthermore, the impact of egg quality on reproductive success has been powerfully established by the continued success of donor oocyte programs. In the USA, the Assisted Reproductive Technology Report for 2003 indicated that the national data from donor oocytes gave rise to a 50% live birth rate, with some clinics reporting live birth rates of over 70%.3