ABSTRACT

The main goal of immunosuppressive therapy is the prevention of rejection while favoring the development of an immunological adaptation. More potent and specific immunosuppressive agents have allowed a significant reduction in the incidence and severity of rejection. However, all the available drugs are associated with a number of side-effects. Their interference with the inflammatory and immune response render the transplant patient more susceptible to infection and neoplasia, which are described in Chapters 9 and 11, respectively. In this chapter, some other specific drug-related complications are described.