ABSTRACT

Figures 3.77, 3.78 Case 1: histology (40×) of an area of the epidermis overlying the BCC shows parakeratosis, mild spongiosis, and minimal focal keratinocytic atypia (circle). RCM (0.45 mm × 0.34 mm) at the level of stratum granulosum/upper stratum spinosum reveals focal loss of the normal honeycomb pattern by bright thickened or effaced intercellular demarcations (asterisks) and focal pleomorphism and disorganization of keratinocytes (red arrows).