ABSTRACT

Cognitive difficulties have been an integral part of the diagnosis of schizo-

phrenia in all diagnostic systems beginning with Kraepelin and Bleuler more

than 100 ago, although they differed on the specific mechanism that was at

fault; thus, Bleuler stressed the loosening of the associational threads that tie

thoughts together, whilst Kraepelin and others emphasized poor attention

and memory difficulties. This chapter describes these difficulties, with

particular reference to the effect they have on quality of life and life choices.

Treatment options for cognitive difficulties in schizophrenia are