ABSTRACT

Blood pressure (BP) is a quantitative trait with a normal, continuous, bell-shaped (Gaussian) distribution pattern, skewed to the upper end in any general population (Figure 2.1), and hypertension represents a clinical definition of the upper part of the distribution curve. Figure 2.1 shows a distribution curve for diastolic BP plotted using BP measurements in 158,906 individuals aged 30-69 years screened for Hypertension Detection and Follow-up Program in the United States (1).