Chronic renal failure and sexual dysfunction

Introduction Erectile dysfunction (ED) is defined as the persistent inability to attain or maintain penile erection sufficient for sexual intercourse. In men with chronic renal failure (CRF), quality of life is significantly impacted by ED. 1,2 The etiology is often multifactorial. Uremia, medications, associated comorbid conditions, physiologic changes with dialysis, and the causative pathophysiology leading to the patient’s CRF should all be considered prior to initiating treatment ( Table 60.1 ). Regardless of the primary cause, ED can have a negative impact on selfesteem, quality of life, and interpersonal relationships.