ABSTRACT

Renal development progresses through three developmental stages: pronephros, mesonephros and metanephros. Human kidney formation originates within the cephalic portion of the intermediate mesoderm, which extends along the entire length of the dorsal body wall of the embryo1. During the late third to early fourth week of gestation, differentiation into pronephros (forekidney) occurs in the cervical region. Soon after, this non-functional collection of clustered cells and tubular-arranged structures degenerates and disappears2.