chapter  4
20 Pages

Effects of exercise on innate immune function

Innate immunity is our first li ne of defence against infectious pathogens. As explained in Chapter 2, the major difference between innate immune responses and adaptive responses is that innate responses do not strengthen upon repeated exposure (there is no memory function). In addition, innate responses are less specific in terms of pathogen recognition. So, whereas innate responses recognise classes of pathogens (e.g. Gram-negative bacteria) through Toll-like receptors (TLRs) , lymphocytes exhibit exquisite specificity for epitopes of individual pathogens (e.g. the influenza virus).