ABSTRACT

Description: Fasturtec or Elitek is a recombinant form of the Aspergillus flaυus urate oxidase, the enzyme that converts uric acid to allantoin. It is produced by recom-binant DNA technology in yeast cells. The biologically active form of the enzyme is a tetramer, consisting of four identical (34-kDa, 301-amino acid) polypeptides. It is supplied in a lyophilized form (1.5 mg/vial) to be reconstituted and diluted before use as an intravenous infusion.