ABSTRACT
Native Americans who greeted Columbus on his arrival in the New World introduced his crew to the use of tobacco, and tobacco use rapidly spread throughout Europe and much of the rest of the world. However, for most of its history tobacco was burned in pipes or cigars and applied to the mucosa in oral or nasal forms.1 The use of tobacco as cigarettes was largely a development of the 20th century (Figure 3.1). The shift toward tobacco use as cigarettes was associated with the introduction of mass marketing techniques by Camel cigarettes in 1913 and the rapid adoption of these techniques by other cigarette manufacturers.2
