ABSTRACT

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Although the pathogenesis of MS remains unknown, the majority of data have favored an autoimmune hypothesis of MS1-3. Therefore, the search for therapeutic strategies in MS has been focused on agents influencing immune system function. Intravenous immunoglobulin (IVIG) represents a non-specific immune therapy which has been successfully applied to a number of autoimmune conditions during the past decade4,5.