ABSTRACT

Jaundice is clinically detectable when the serum bilirubin exceeds 85 µmol/l and, in the older infant or child, often indicates serious underlying pathology. Jaundice is said to be conjugated if the conjugated fraction of the total bilirubin is more than 15%. Bilirubin will then be present in the urine, which will be dark, and absent in the stool, which will be pale in colour. Neonatal jaundice is discussed in a separate chapter.