ABSTRACT

Peripheral nerve disorders may affect sensory and/or motor nerves, involving one nerve (mononeuropathy) or causing a more generalized neuropathy (polyneuropathy). A neuropathy can present acutely (e.g. foot drop, facial palsy) or more chronically with muscle wasting and weakness. Sensory nerve involvement results in paraesthesia or anaesthesia, typically of the hands and feet. Neurophysiology shows slowed nerve conduction velocity and muscle biopsy may show denervation.