ABSTRACT

It is now recognized that a variety of anthropogenic environmental contaminants can interfere with development of the brain and reproductive system in wildlife and humans by interfering with neural and endocrine signals and other cellular functions, such as enzyme activity. These environmental chemicals are referred to as endocrine disruptors (Colborn et al., 1993). The primary focus of the research we will describe is on behavioral effects of endocrine-disrupting chemicals that mimic the action of estrogen, emphasizing consequences of exposure to low, environmentally relevant doses during critical periods in brain and organ development.