ABSTRACT

Introduction The use of permanently implanted metallic stents in the urinary tract started after it was demonstrated that woven mesh stents constructed of small-diameter biocompatible wire in the dog urethra would become covered with urothelium in exactly the same way that Sigwart et al.1 had earlier demonstrated the rapid covering of endovascular stents by endothelium when placed in the lumen of blood vessels. The early experimental work on the dog urinary tract was carried out jointly by Milroy2 and Sarramon,3 and this important finding of stent epithelial covering opened the way for the use of these devices in the human urinary tract, in the knowledge that, once the metallic stent had become covered with epithelium, there would be no contact of the metal wires with urine, and thereby avoiding the inevitable consequence of the encrustation, stone formation and infection that occurs when any foreign material is left in contact with urine.