ABSTRACT

GABA Cerebellum, cerebral cortex, presynaptic inhibitors, retina

? There are receptors on the pre-as well as the postsynaptic elements at many synaptic junctions. The presynaptic receptors (also called autoreceptors) often inhibit further secretion of the transmitter, providing feedback control. This is, for

Adenosine Neocortex, olfactory cortex, hippocampus, cerebellum

ATP Not established

Polypeptides

Substance P Ubiquitous, retina

Vasopressin Posterior pituitary, medulla, spinal cord

Oxytocin Posterior pituitary, medulla, spinal cord

CRH Median eminence of hypothalamus, other parts of brain

TRH Median eminence of hypothalamus, other parts of brain, retina

GRH Median eminence of hypothalamus

Somatostatin Median eminence of hypothalamus, other parts of brain, retina

GnRH Median eminence of hypothalamus, circumventricular organs, retina

Endothelins Posterior pituitary, brain stem

Enkephalins Ubiquitous, retina

ß-Endorphin Hypothalamus, thalamus, brain stem, retina

CCK Cerebral cortex, hypothalamus, retina

VIP Postganglionic cholinergic neurons, hypothalamus, cerebral cortex, retina

Neurotensin Hypothalamus, retina

GRP Hypothalamus

Gastrin Hypothalamus, medulla oblongata

Glucagon Hypothalamus, retina

Motilin Neurohypophysis, cerebral cortex, cerebellum

Secretin Hypothalamus, thalamus, olfactory bulb, brain stem, cerebral cortex, hippocampus

CGRPa Taste pathways, medial forebrain bundle

Neuropeptide Y Medulla, periaqueductal grey, hypothalamus

Activins Brain stem

Inhibins Brain stem

Angiotensin II Hypothalamus, brain stem, spinal cord

Galanin Hypothalamus

ANP Hypothalamus, brain stem

BNP Hypothalamus, brain stem

However, autoreceptors can also facilitate the release of neurotransmitters.