ABSTRACT

Age-related macular degeneration is the leading cause of blindness in people over the age of 50 in the Western world. There are two types of age-related macular degeneration: nonneovascular (dry) and neovascular (wet). Neovascular age-related macular degeneration is characterized by the presence of choroidal neovascularization. Choroidal neovascularization is the predominant cause of severe visual loss in age-related macular degeneration. Within 5 years of onset of choroidal neovascularization, 75% of eyes fulfil the criteria for blind registration.