ABSTRACT
Although atherosclerosis in patients with diabetes is similar to that seen in nondiabetics, it is generalized, occurs prematurely and progresses at an accelerated pace. Coronary artery, cerebrovascular and peripheral vascular disease (PVD) are the predominant manifestations of macrovascular disease in diabetes. Majority of patients with PVD have associated coronary artery disease, however the opposite is not true. This is perhaps because the clinical manifestations of PVD occur almost a decade later than those of coronary artery disease. In fact the disease of posterior tibial artery commonly seen in diabetics, is a surrogate marker of coronary artery disease.
