ABSTRACT
Wound healing is the process by which tissues respond to an injury. The process of wound healing is controlled by growth factors that initiate cell growth and proliferation by binding to specific high-affinity receptors on the cell surface. Growth factors have the ability to stimulate the mitosis of quiescent cells. They are produced by platelets, macrophages, epithelial cells, fibroblasts and endothelial cells. The growth factors most commonly involved in wound healing include plateletderived growth factor (PDGF), fibroblast growth factor (FGF), epidermal growth f actor (EGF) and insulin like growth factor (IGF).
