ABSTRACT

Given the current limitations on anti-HIV drugs, it seems logical to attack the problem from other directions as well. The second part of this chapter will focus on the development of vaccines to prevent HIV infection. For those who already have the infection, improved adjuvants and the production of many immunological cytokines by recombinant technology means that directed immunomodulation is now possible. This could be used in two ways in established HIV infection: to improve the host’s own immune response to the virus; and to restore the defective cellular immunity.