ABSTRACT

The history of the treatment of cervix cancer is linked to some of the most important advances in oncology in the twentieth century. Cervix cancer was the first solid tumor cured by radiotherapy In the 1920s, the fundamentals of brachytherapy for cervix cancer were developed. The cervix is a relatively radioresistant organ, and the uterus and vagina can be used to hold instruments loaded with radioactive sources very close to the primary tumor. Because of the inverse square law, which states that dose drops off at a rate of one divided by the square of the distance from a point source, the dose to the bladder and rectum with brachytherapy is tolerable.