ABSTRACT

Acetaminophen, salicylates (aspirin), and nonsteroidal anti-inßammatory agents are found alone and in combination with other analgesic/antipyretic* compounds, in hundreds of over-the-counter (OTC) and prescription formulas. As such, these agents are routinely reported as products responsible for acute and chronic overdose, with acetaminophen accounting for the most poisoning cases within this category. Packaging laws and public service education campaigns have reduced the frequency of accidental poisoning, especially in children and teenagers. Because the drugs are available OTC, however, it suggests that these agents are innocuous, although they are marketed with clearly marked warnings and suggestions for use.