ABSTRACT

Providing a cutting-edge profile of research progress in this important field of study, Cholinergic Mechanisms: Function and Dysfunction contains a compilation of the proceedings of the Eleventh ISCM, held in St. Moritz, May 2002. Bringing together 250 contributors from 30 countries, the book presents a comprehensive picture of the cholinergic field. It provides a survey of current understanding of molecular, pharmacological, toxicological, behavioral, and clinical aspects of the cholinergic system. This volume offers a state-of-the-art account of progress in the field from the molecule in the test tube through the cell and the synapse, to the organism and the patient.

Nicotinic Receptors: Structure. Muscarinic Receptors: Structure. Couteaux Lecture. Presynaptic Mechanisms. Structural and Regulatory Aspects of the Cholinergic Synapse. Structural and Functional Studies on Cholinesterases. The Cholinergic System in Invertebrates. Autoimmune Diseases Related to the Cholinergic Synapse. Toxicology and Pharmacology of Cholinesterase Inhibitors. Brzin Lecture. Pharmacology of Nicotinic and Muscarinic Receptors in the CNS. Cholinergic-Amyloid Cross-Talk. Cholinergic Pathways and Regulation in the CNS. Clinical Studies on Alzheimer Patients. Closing Session. Poster Presentations.