ABSTRACT
The combined oral contraceptive pill has long been known to incur an increased risk of venous thrombosis. The first case report occurred in 1961, when a nurse developed a pulmonary embolism after starting the oral contraceptive pill containing 100 µg of mestranol for endometriosis171. In the subsequent 40 years, there have been a variety of reports on the association between the combined oral contraceptive pill and venous thrombosis, including case reports or descriptive studies, case-control studies and prospective cohort studies.
