ABSTRACT

Endometriosis is the presence outside the uterus of tissue which somewhat resembles endometrium from the uterine lining. It affects approximately 10% of the female population in their reproductive years and may cause non-menstrual or menstrual pain as well as infertility. The most widely held theory of origin is Sampson’s theory of reflux menstruation. Sampson’s final version of his theory1 proposed that endometriosis occurs as a result of the reflux of menstrual blood out through the end of the fallopian tubes, this blood carrying with it viable cells from the endometrial lining which could attach to peritoneal surfaces, proliferate, invade, and become the disease known as endometriosis.