ABSTRACT
On 9 July 2002, the announcement of the termination of the estrogen/ progestin (Prempro™) arm of the Women’s Health Initiative (WHI) created a frenzy among menopausal women worldwide. For many, there was a belief that this was the first and only study of estrogen use to have been conducted, and that the results showed devastating effects on Prempro users. We as healthcare providers have an obligation to put this study into proper perspective for our patients, and to continue to assess new data as it becomes available in order to care for our patients properly. A brief history of estrogen use will therefore be helpful.
