ABSTRACT
Rate constant matrix (rcm): this is constructed by drawing a square grid with n × n cells, where n is the total number of enzyme forms (free enzyme plus complexes) in the reaction scheme. On the left, adjacent to the first column, form a list down through each enzyme form, placing the names at consecutive rows with an arrow facing left to right after each name; this labels each "from" row. Then, across the top of the first row write the names of each enzyme form, in the same order as used for the first column. Before each enzyme name place an arrow facing left to right; this labels the "to" columns. Refer to the enzyme reaction scheme and place the relevant rate constant, together with any relevant reactant symbol, in the appropriate grid location. Note that a zero appears in all cells at the intersection of a "from" row with the "to" column of the same species. See also Section 3.4.2 for a description of this matrix.
