ABSTRACT
Delayed cerebral vasospasm (DCV) is the leading cause of morbidity and mortality in patients who have ruptured intracranial aneurysms and are admitted to tertiary care centers.1,2 Thick focal collections of blood visualized on a CT scan are highly predictive of the risk of DCV.3,4 The time course of the event is well established,5 although the pathophysiology has remained a puzzle for many years. Recent advances in cellular and molecular biology techniques have led to the development of new hypotheses regarding this very important clinical problem.
