ABSTRACT

Introduction ..........................................................................................................107 Anticarcinogenicity of Broccoli ...........................................................................108 Phase I and Phase II Detoxification Enzymes .....................................................110 Monofunctional and Bifunctional Induction ........................................................110 The Xenobiotic Response Element and Indole-3-Carbinol .................................111 The Antioxidant Response Element, Sulforaphane, and Crambene ...................112 Activation of Transcription Factors Associated with the ARE ...........................113 Quinone Reductase Is Regulated by Both an XRE and an ARE ........................114 Summary ...............................................................................................................115 References ............................................................................................................115