ABSTRACT
Contributors ................................................................................................................................................ vii
Introduction ................................................................................................................................................ xi
SECTION I HOST DEFENSES
1. Treatment strategies for solid tumors and impact on host defenses Margret Merino and Crystal L Mackall .............................................................................................. 3
2. Treatment strategies for hematological malignancies: Impact on host defenses and infection risk Ivana Gojo, Clarence B Sarkodee-Adoo, Roger R Hakimian, William G Merz and Judith E Karp ...... 17
3. Blood and marrow transplantation Leona Holmberg ................................................................................................................................ 37
SECTION II INFECTIOUS SYNDROMES
4. Infectious syndromes in solid tumor therapy James A Talcott and John R Wingard ................................................................................................ 55
5. Infectious complications in patients receiving cytotoxic therapy for acute leukemia: History, background and approaches to management Eric J Bow .......................................................................................................................................... 71
6. Infections in chronic leukemias and other hematological malignancies Farhad Ravandi, Elias Anaissie and Susan O’Brien ............................................................................ 105
7. Infections in hematopoietic stem cell transplant patients Elizabeth Reed.................................................................................................................................... 129
SECTION III MANAGEMENT STRATEGIES
8. Infections caused by gram-positive cocci and gram-negative rods Jacob Strahilevitz and Dan Engelhard ................................................................................................ 147
9. Management strategies for infections caused by Candida species
10. Invasive aspergillosis complicating neoplastic diseases and hematopoietic stem cell transplantation Thomas J Walsh and Kieren A Marr .................................................................................................. 179
11. Fungi other than Candida and Aspergillus Pranatharthi H Chandrasekar ............................................................................................................ 203
12. Management strategies for herpes simplex viruses in cancer patients and hematopoietic stem cell transplant recipients Richard J Whitley .............................................................................................................................. 223
13. Management strategies for varicella-zoster infections in patients with cancer Paula W Annunziato and Anne A Gershon ........................................................................................ 233
14. Management of CMV infection in hematopoietic stem cell transplant recipients Morgan Hakki and Michael Boeckh .................................................................................................. 247
15. Epstein-Barr virus infections in the oncology patient Farid Boulad, Diane George, Trudy N Small and Richard J O’Reilly.................................................. 269
16. Respiratory viruses in immunocompromised hosts Laurent Kaiser.................................................................................................................................... 287
17. Hepatitis virus infections in patients with cancer George KK Lau, Simone I Strasser and George B McDonald.............................................................. 321
SECTION IV OTHER THERAPIES
18. Use of hematopoietic growth factors in the management of infection in oncology patients Dean McGaughey and Jeffrey Crawford ............................................................................................ 345
19. Granulocyte (neutrophil) transfusion therapy W Conrad Liles, Kai Hubel and David C Dale .................................................................................. 363
20. Uses of immunoglobulins in the management of infection in oncology patients Helen Leather .................................................................................................................................... 373
21. Infection control Gianna Zuccotti and Kent Sepkowitz ................................................................................................ 405
22. Vaccinations in oncology patients Per Ljungman .................................................................................................................................... 417
23. Transfusion considerations Lawrence T Goodnough and John F DiPersio .................................................................................... 431