ABSTRACT
The dystonia genetic loci and genes are summarized in Tables 3.2-3.4. The molecular classification is somewhat complex and confusing and contains mapped loci, cloned genes including primary dystonia, dystonia-plus syndromes (dopa-responsive dystonia, myoclonus-dystonia syndrome, and rapid-onset dystonia-parkinsonism) and one heredodegenerative condition (X-linked dystoniaparkinsonism). Within this classification, two loci (DYT2 and DYT4) have been assigned on the basis of clinical descriptions alone. It is clear that there are other dystonia genes yet to be discovered.
