ABSTRACT

Oocyte donation is being practiced for about two decades in human infertility treatment. In 1984, Lutjen et al1 reported the first pregnancy and delivery following in-vitro fertilisation and embryo transfer (IVF and ET) in a patient with primary ovarian failure. A woman who is unable to produce her own oocytes due to malfunctioning, nonfunctioning or absent ovaries receives the oocytes. Oocyte donation is an emotional, expensive and time-intensive experience, but it offers a realistic, successful, option for many couples who would otherwise have no way to have a child. It is important to remember that each patient has her own unique response to the medication she receives and that each assisted reproductive technique (ART) cycle is different. In clinical practice not only is an individual likely to respond differently from others, but also one may actually respond differently from one cycle to the next. For this reason, treatment and testing differs in each patient and possibly on each occasion.