ABSTRACT

Ovulation induction for infertility treatment with or without assisted reproductive technologies such as insemination and in vitro fertilisation has resulted in a phenomenal increase in high order (three or more) multiple pregnancies.1,2,3,4

Perinatal mortality and morbidity are directly proportional to the number of fetuses5 and are also largely consequent to the high incidence of premature deliveries6 in multifetal pregnancies. Although earlier diagnosis, increased antenatal surveillance and improved neonatal care have improved pregnancy outcomes, the overall prognosis of multiple pregnancy with four or more fetuses is pathetic. Even in triplet pregnancies, the incidence of long term neurologic deficits and recurrent hospitalisation in inf ancy is high as is neonatal and inf ant mortality when compared to twin gestations.